Host-Pathogen Interactions

The divison covers the investigation of various bacterial pathogens of animal diseases including zoonoses.

The work covers:

  • Development and improvement of vaccines using state of the art synthetic genomics tools and classical techniques
  • Development and improvement of diagnostic assays
  • Research on bacterial virulence traits and their interactions with the host
  • Research on bacterial diseases of the hoof, claws and the skin including taxonomic studies and typing
  • Focus bugs: Mycoplasma spp., Pasteurellaceae, Dichelobacter spp.


Extramural research funds (last 5 years):

1.            Donor: National Science Foundation (USA); Project title: ‘Special creative extension related to the project BREAD: Toward Development of a Vaccine for Contagious Bovine Pleuropneumonia’; Total budget US$1,879,282; Project duration: 8/2015 - 4/2019; Principal investigator: Sanjay Vashee, J. Craig Venter Institute (USA), Co- Principal Investigator: Jörg Jores, University of Bern (Switzerland), Co-Principal Investigator: Carole Lartigue and Pascal Sirand-Pugnet, INRA (France); IVB Project staff: Jörg Jores, Fabien Labroussaa, Valentina Cippa, Melanie Schumacher

2.       Donor: Vaccine challenge fund from IDRC (Canada); Project title: ‘Development of a novel vaccine for contagious caprine pleuropneumonia based on a fast-growing Mycoplasma feriruminatoris chassis’; Total budget: 1,400,000 CAD; Project duration: 11/2017-2/2020; Principal investigator: Jörg Jores: Co-Principal Investigator: Carole Lartigue and Pascal Sirand-Pugnet, INRA (France); Partner institution: J. Craig Venter Institute (USA); IVB Project staff: Jörg Jores, Fabien Labroussaa, Valentina Cippa, Milena Tresch

3.            Donor: Horizon2020 "SAPHIR" (European Union) Project title: 'Development of a Mycoplasma hyopneumoniae attenuated vaccine and improvement of bacterin vaccine'; IVB Budget 212,500 €; Duration 3/2015 - 2/2019; Principal investigator: Dominique Maes University of Ghent (Belgium); Co-principal investigator: Peter Kuhnert, Partner institutions: EDI-IVI (Switzerland), University of Ghent (Belgium); IVB Project staff: Peter Kuhnert, Bettina Trueb, Simona Gerber

4.            Donor: Federal Food Safety and Veterinary Office FSVO (Switzerland); Project title: 'In-vitro and ex-vivo testing of the suitability of different disinfecting solutions for use in footbaths in the planned Swiss footrot control program', Budget: CHF 116'347; Project duration: 1/2018-6/2019, Principal investigator: Adrian Steiner, University of Bern (Switzerland), Co-investigator: Peter Kuhnert; IVB Project staff: Peter Kuhnert, Tobias Hidber

5.            Donor: Swiss National Science Foundation, Project title: Project title: ' Mycoplasmas and hosts: activation and protective niches'; Total budget 372,000 CHF; Duration 6/2015 - 7/2018; Principal investigator: Paola Pilo; IVB Project staff: Paola Pilo, Christoph Josi, Sara Vidal

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